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Seek immediate medical attention for signs of a severe allergic reaction including hives, swelling of the face, lips, tongue, or throat, difficulty breathing, or chest tightness

[137] Laboratory [edit] The complete laboratory synthesis of B 12 was achieved by Robert Burns Woodward [138] and Albert Eschenmoser in 1972

Infection Skipping skin cleaning or reusing a needle can introduce bacteria

These tests not only measure B12 levels but also help identify potential underlying causes of deficiency

Moreover, insulin-like growth factor binding protein related proteins (IGFBPrPs) have been recently characterised, which aid the metabolic effects of the hormone but their role remains unclear [96, 97]